In Depth Look at Rising Incidence of Colon Cancer in Younger Patients

Course Overview

Objectives:

1. Identify the possible causes/changes in our society leading to younger patients with colon cancer.
2. Importance of gut microbiome and the effects of diet and lifestyle that can alter it, leading to cancer.
3. Recall the signs and symptoms of colon cancer and it is different in younger patients.
4. Advances in colorectal cancer treatment.

Needs:

1. Advances in medical knowledge
2. New methods of diagnosis or treatment

References:

1. 1. Exploring the Inflammatory pathogenesis of colorectal cancer, Diseases 2021, 9(4), 79; https:??doi.org/10.3390/diseases9040079

2 Hadjipetrou, A.; Anyfantakis, D.; Galanakis, C.G.; Kastanakis, M.; Kastanakis, S. Colorectal cancer, screening and primary care: A mini literature review. World J. Gastroenterol. 2017, 23, 6049-6058.

3.Kedrin, D.; Gala, M.K. Genetics of the Serrated Pathway to Colorectal Cancer. Clin. Transl. Gastroenterol. 2015, 6, e84.

4.BMJ 2022; 378 doi: https://doi.org/10.1136/bmj-2021-068921 (Published 31 August 2022)

5.Luo, C.; Zhang, H. The Role of Proinflammatory Pathways in the Pathogenesis of Colitis­ Associated Colorectal Cancer. Mediat. lnflamm. 2017, 2017, 1-8.

6.Mantovani, A.; Sica, A. Macrophages, innate immunity and cancer: Balance, tolerance, and diversity. Curr. Opin. lmmunol. 2010, 22, 231-237.

7.The American Journal of Gastroenterology 119(10S):p S288, October 2(L2!t I DOI: 10.14309/01.ajg.0001030988.63838.f9

8.Nutrients 2023 Jan 25:; 15(3) 617

Core Competencies: 2,3,5,6,7